Jofrati.net - PR 4 Dofollow Social Bookmarking Site - C actions of relaxin are completely abolished by the AT2R http://jofrati.net/story/1074439/ C actions of relaxin are completely abolished by the AT2R antagonist PD123319 (Chow et al., 2014). In an in vivo fibrosis model in mice, produced by unilateral ureteric obstruction, the protective effects of relaxin are lost when the AT2R is either absent (in AT2R2/y mice) or blocked by PD123319, confirming that the AT2R is obligatory for the antifibrotic actions of relaxin. These effects are not Fri, 16 Aug 2019 11:11:39 UTC en