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Of the Meckel's cartilage, the distance between the two pupils and the width of the hyosymplectic cartilage (Supplementary Figure 7). The Meckel's cartilage forms the U-shape of the lower jaw, while the hyosymplectic cartilage supports the jaw [44]. The distance between the two hyosympletic cartilages for all embryo groups did not show a statistically significant difference (the range was from 481

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