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S free of relevant side effects.Relaxin Family Peptide ReceptorsThe use of relaxin for acute heart failure (defined as new onset or, more frequently, worsening of known heart failure) is promising. In the Pre-RELAX (phase II) and RELAX (phase III) trials (Teerlink et al., 2009, 2013), relaxin moderately improved dyspnea (the primary endpoint), was exceptionally safe, improved renal function, and l

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