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Ributed to relaxin (Heeg et al., 2005; Mookerjee et al., 2009; Chow et al., 2012), including inhibition of the TGF-b1/pSmad2 axis and reduced TGF-b1 nduced collagen deposition. Because AT2Rs are expressed at low levels in tissues (Matsubara, 1998; Carey, 2005; Jones et al., 2008) and fibroblasts under physiologically quiescent states but are dramatically increased in number and activity under path

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