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AngII endorsed the increase involving [Ca2+]i inside GMCs, which in turn brought on their spreading. The procedure through which this happens commences with your binding involving AngII for you to AT1R on the surface associated with GMCs, which then causes phospholipase h (PLC) to be able to catalyze the particular cleavage of four,5-phosphatidyl inositol diphosphate (PIP2), generating 1,Several,5

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