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Upon activation simply by receptor binding, RAS meats sign up Royal air force towards the mobile tissue layer in which RAF can be phosphorylated [2]. Initialized RAF proteins additional phosphorylate MEK1 and also MEK2, which phosphorylate ERK1 and ERK2. Phosphorylated ERK proteins regulate cell capabilities by way of activation involving transcribing elements such as p53, SMAD4, ELK1, c-Myc and c

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