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Ddition, overexpression of membranebound IL-1 at the surface of fibrosarcoma or lymphoma cell lines induced loss of tumorigenicity. Once injected into mice, such cells form tumors that rapidly regress or cannot grow.185?87 Furthermore, after injection into wild-type (WT) mice, these cells induced the appearance of a longterm memory against tumor cells that relied on the infiltration of CD8+ T cell

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