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S that are up-regulated by BaP in Oikopleura are shown in blue color. AhR and CYP1 are crossed out in red to show the absence of the genes in Okopleura genome. Solid black arrows indicate biotransformation such as binding, activation and transport. Dotted black arrows indicate increase in transcript or protein synthesis. Solid blue arrows indicate activation of transcription factors through MAPK s

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